“Yes, if medically justified and there is sufficient tissue compatibility between donor and recipient. There is a 25% probability that the tissue antigens of siblings are fully compatible.”
“Yes. The results of many studies indicate that stem cells derived from cord blood are more primary, less targeted, and have a higher proliferative dynamics compared to stem cells derived from adult bone marrow or peripheral blood.”
“Matching donor and recipient marrow is very difficult, as a so-called “full match” is usually required. “full compatibility”. Stem cells from cord blood are characterized by less immunological “maturity”, so their transplantation causes fewer complications in the recipient (in the case of allogeneic transplantation, it’s a lower risk of rejection and a less pronounced “graft versus host” reaction).”
“The WMDA (World Marrow Donor Association) organization, which coordinates the collection of data on, among other things. about volunteers and hematopoietic cell donors states on its website that more than 35,000 cord blood transplants have been performed in both children and adults.”